TacroliMus 8-Propyl Analog (USP)
dihydro-fk 506
CAS: 104987-30-6
Molecular Formula: C44H71NO12
TacroliMus 8-Propyl Analog (USP) - Names and Identifiers
| Name | dihydro-fk 506 |
| Synonyms | Dihydro-FK506 dihydro-fk 506 TsukubaMycin B Dihydro-FK506 DIHYDRO-FK506 TacroliMus 8-Propyl Analog (USP) Tacrolimus EP Impurity E (Dihydro Tacrolimus) 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-propyl-, (3S,4R,5S,8R,9E,12S,14S,... |
| CAS | 104987-30-6 |
| EINECS | 806-466-9 |
| InChI | InChI=1S/C44H71NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h19,21,26,28-34,36-40,46-47,52H,10-18,20,22-24H2,1-9H3/b25-19+,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1 |
TacroliMus 8-Propyl Analog (USP) - Physico-chemical Properties
| Molecular Formula | C44H71NO12 |
| Molar Mass | 806.03 |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Melting Point | 87-94°C |
| Boling Point | 875.5±75.0 °C(Predicted) |
| Solubility | Soluble in DMSO |
| Appearance | White powder |
| pKa | 9.97±0.70(Predicted) |
| Storage Condition | 2-8℃ |
TacroliMus 8-Propyl Analog (USP) - Risk and Safety
| HS Code | 2934990002 |
TacroliMus 8-Propyl Analog (USP) - Introduction
Tacrolimus Impurity 6, also known as Tacrolimus EP Impurity E or Tacrolimus 8-Propylene Analog, is a chemical compound that is closely related to the immunosuppressant drug Tacrolimus (also known as FK506). It is categorized as an impurity, which means it is an unintended product or byproduct that can be found during the manufacturing process of Tacrolimus.
As an analog of Tacrolimus, Tacrolimus Impurity 6 shares a similar chemical structure but may have slightly different properties and effects. It is primarily used for analytical purposes in pharmaceutical research and development. Researchers utilize impurities like Tacrolimus Impurity 6 to identify, analyze, and quantify the impurities present in Tacrolimus formulations.
It is important to note that Tacrolimus Impurity 6 should not be used for human consumption or as a therapeutic agent, as its safety and efficacy have not been established for such purposes. Instead, its significance lies in its role as a reference standard, helping researchers ensure the quality, purity, and potency of Tacrolimus drugs on the market.
In summary, Tacrolimus Impurity 6 (Tacrolimus EP Impurity E or Tacrolimus 8-Propylene Analog) is an impurity commonly detected in Tacrolimus formulations. It serves as a reference standard for research purposes, allowing scientists to study and monitor impurities in order to ensure the quality of Tacrolimus medications.
Last Update：2024-04-09 19:05:42
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View History
TacroliMus 8-Propyl Analog (USP)
4-(((2-氯嘧啶-5-基)氧基)甲基)哌啶-1-羧酸叔丁酯
N-[2-[(4-AMINO-3-METHYLPHENYL)ETHYLAMINO]ETHYL]METHANESULFONAMIDE SESQUISULFATE MONOHYDRATE
苄基二(2-羟乙基)甲基氢氧化铵
1-叔丁基二甲硅基咪唑[叔丁基二甲基硅化剂]
2-(3-硝基苯亚甲基)-3-氧代丁酸(2-甲氧基乙基)酯
Benzaldehyde, 4-[(2-methoxyethoxy)methoxy]-
(ALPHAS)-ALPHA-氨基环己烷丁酸
CUPRIC CHLORIDE DIHYDRATE ACS REAGENT
4-氰基吡啶 N-氧化物(托匹司他中间体)
4-(((2-氯嘧啶-5-基)氧基)甲基)哌啶-1-羧酸叔丁酯
N-[2-[(4-AMINO-3-METHYLPHENYL)ETHYLAMINO]ETHYL]METHANESULFONAMIDE SESQUISULFATE MONOHYDRATE
苄基二(2-羟乙基)甲基氢氧化铵
1-叔丁基二甲硅基咪唑[叔丁基二甲基硅化剂]
2-(3-硝基苯亚甲基)-3-氧代丁酸(2-甲氧基乙基)酯
Benzaldehyde, 4-[(2-methoxyethoxy)methoxy]-
(ALPHAS)-ALPHA-氨基环己烷丁酸
CUPRIC CHLORIDE DIHYDRATE ACS REAGENT
4-氰基吡啶 N-氧化物(托匹司他中间体)